Similar to a mechanical device that wears out faster with heavy use, so also does the depth of discharge (DoD) determine the cycle count. The smaller the depth of discharge, the longer the battery will last.Interestingly, this goes against Apple's recommendation that iPad owners perform a full charge-and-discharge cycle on their batteries once a month.
If at all possible, avoid frequent full discharges and charge more often between uses. If full discharges cannot be avoided, try utilizing a larger battery. Partial discharge on Li-ion is fine; there is no memory and the battery does not need periodic full discharge cycles other than to calibrate the fuel gauge on a smart battery.
(Via Lifehacker.)